- Cdh1 Mutants
- cdh1∆
- sic1∆ cdh1∆
- sic1∆ cdh1∆ GALL-CDC20
- sic1∆ cdc6∆2-49 cdh1∆
- sic1∆ cdc6∆2-49 cdh1∆ GALL-CDC20
- cdh1∆ cdc6∆2-49
- swi5∆ cdh1∆
- swi5∆ cdh1∆ GAL-SIC1
- cln1∆ cln2∆ cdh1∆
- GAL-CLN2 cln1∆ cln2∆ cdh1∆
- cln1∆ cln2∆ cln3∆ cdh1∆
- GAL-SIC1 cln1∆ cln2∆ cdh1∆
- GAL-SIC1 GAL-CLN2 cln1∆ cln2∆ cdh1∆
- CLB1 clb2∆ cdh1∆
- GAL-CLB2 cdh1∆
- GAL-CLB5 cdh1∆
- cdc14-ts cdh1∆
- cdc15∆ net1-ts cdh1∆
- APC-A cdh1∆
- APC-A cdh1∆ in galactose
- APC-A cdh1∆ GAL-SIC1
- APC-A cdh1∆ GAL-CDC6
- APC-A cdh1∆ multi-copy SIC1
- APC-A cdh1∆ multicopy CDC6
- APC-A cdh1∆ multicopy CDC20
- Cdh1 constitutively active
GAL-CLN2 cln1∆ cln2∆ cdh1∆
debug: ,
test user =
test db =
Simulation:
Change of parameters: ksn2'=0.12, ksn2"=0, kscdh=0, MDT=150, init CDH1T=CDH1=0.
Length of G1 phase: 153.7 min.
Mass at division: 0.61.
Experiments:
Cross, F.R., Archambault, V., Miller, M., Klovstad, M. (2002). Testing a mathematical model of the yeast cell cycle. Mol. Biol. Cell 13:52-70.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Fig. 3B, viable.
Comments: In our simulation, [BUD]max=0.5 <1, we suppose the morphogenesis
checkpoint
(Lew, 2000;
Ciliberto et al, 2003)
would cause a delay in mitosis.